Approaching the Bio-Engineer profession starts out by requiring organic chemistry from the Novice Medic Profession, Hunting from Scout and 10,000 additional medicine crafting XP. Once the novice Bio-Engineer Profession is acquired, a player will have to start thinking about their laboratory, their tools and their trade.

The first thing a BE needs is a Food and Chemical Crafting Tool. With this tool, you will be able to begin crafting. You will be able to craft this tool with the Novice Medic skill and this schematic is also granted with Engineering I: Tinkering. Once you have this tool, it will gain you access to Food and Chemical Crafting Stations. These crafting stations, which have both public and private versions, are passive components to the process. Use your food and chemical crafting tool near these stations to be granted more and more crafting schematics as you progress through the profession. You must be in close proximity to the station to benefit from the effect of working with the equipment. Public crafting stations will get you started, but you will soon find yourself wanting your own private station, as higher-level schematics will not work with public stations. Private crafting stations of a high quality will also produce much better results than a public crafting station. Another "must have" tool to the process is a droid crafting station. Ever useful in the field, these little droids make a Bio-Engineer's life much easier since they function as a private crafting station.

Another angle to consider is that, as a hybrid profession, a Bio-Engineer can take other skills outside the profession to customize the experience and make it their own. Some considerations are creature handling, so you can make and use your own high level pets. The Ranger tracking line can be helpful for locating specific creatures. Many Bio-Engineer's also take Exploration IV as it's indispensable for sneaking up on an aggressive creature in the wild.